Introduction: Acute disseminated encephalomyelitis ADE is an inflammatory disorder of the central nervous system that is mediated immunologically and of unknown pathogenesis. It can present at any age, but is much more frequent in children. ADE has no specific biological marker and diagnosis is based on findings from clinical and neuroimaging studies. Aim: To enhance our knowledge of the clinico-radiological profile of this disease.
|Published (Last):||1 December 2009|
|PDF File Size:||17.67 Mb|
|ePub File Size:||10.30 Mb|
|Price:||Free* [*Free Regsitration Required]|
Introduction: Acute disseminated encephalomyelitis ADE is an inflammatory disorder of the central nervous system that is mediated immunologically and of unknown pathogenesis. It can present at any age, but is much more frequent in children. ADE has no specific biological marker and diagnosis is based on findings from clinical and neuroimaging studies.
Aim: To enhance our knowledge of the clinico-radiological profile of this disease. Patients and methods: This retrospective study involved patients under 14 years of age who were admitted to a tertiary hospital over the last 15 years with a diagnosis of ADE.
In 16 cases an average follow-up of 25 months was performed. Forty per cent had a previous febrile episode. Three children progressed with relapses and three others were left with motor sequelae. Haemorrhagic ADE was diagnosed in two patients. Conclusions: ADE is a condition with an important degree of general involvement and neurological repercussions, as well as considerable potential to leave the patient with sequelae.
Clinico-analytical data and magnetic resonance scans of the head and spinal cord are relevant for the initial diagnosis and follow-up of patients with ADE. Title: Perfil clinicorradiologico de la encefalomielitis aguda diseminada en la poblacion infantil. Analisis retrospectivo de una serie de 20 pacientes de un hospital terciario.
La encefalomielitis aguda diseminada EAD es un trastorno inflamatorio del sistema nervioso central mediado inmunologicamente y de patogenia desconocida. La EAD no tiene marcador biologico especifico y el diagnostico se basa en hallazgos clinicos y neurorradiologicos.
Mejorar el conocimiento del perfil clinicorradiologico de esta enfermedad. Pacientes y metodos. En 16 casos se realizo un seguimiento medio de 25 meses. En dos pacientes se diagnostico EAD hemorragica. La EAD representa una entidad con importante afectacion general y repercusion neurologica, que muestra un potencial secuelar considerable. Los datos clinicoanaliticos y la resonancia magnetica cerebral y medular son relevantes para el diagnostico inicial y seguimiento de pacientes con EAD.
Name your collection: Name must be less than characters. Choose a collection: Unable to load your collection due to an error Please try again. Add Cancel. Add to My Bibliography My Bibliography. Unable to load your delegates due to an error Please try again. Your saved search Name of saved search:. Search terms:. Test search terms. Would you like email updates of new search results?
Email: change. Frequency: Monthly Weekly Daily. Which day? Send at most: 1 item 5 items 10 items 20 items 50 items items items. Send even when there aren't any new results.
Optional text in email:. Save Cancel. Create a file for external citation management software Create file Cancel. Full-text links Cite Favorites. Abstract in English , Spanish.
Similar articles [Analysis of a series of cases with an initial diagnosis of acute disseminated encephalomyelitis over the period ]. Rev Neurol. Therapeutic plasma exchange in acute disseminated encephalomyelitis in children. Borras-Novell C, et al. J Clin Apher. Epub Aug PMID: Evaluation of the cases with acute disseminated encephalomyelitis.
Tosun A, et al. Indian J Pediatr. Epub Apr Charpentier P, et al. Rev Med Liege. PMID: Review. Case mix review over a 13 year period]. Show more similar articles See all similar articles. Publication types English Abstract Actions. Adolescent Actions. Child Actions. Child, Preschool Actions. Comorbidity Actions. Diagnosis, Differential Actions. Female Actions. Humans Actions. Infant Actions. Magnetic Resonance Imaging Actions.
Male Actions. Plasmapheresis Actions. Retrospective Studies Actions. Symptom Assessment Actions. Substances Adrenal Cortex Hormones Actions. Cerebrospinal Fluid Proteins Actions.
Immunoglobulins, Intravenous Actions. Acyclovir Actions. Full-text links [x] Viguera Editores, S. Copy Download.
2010, Número 593
Introduction: Acute disseminated encephalomyelitis ADEM is a demyelinating disease that essentially affects the white matter of the central nervous system. The diagnosis is based on clinical-imaging and developmental findings. Magnetic resonance imaging of the brain is the most useful diagnostic tool. The disease course is usually monophasic and the preferred initial treatment is with corticoids. Patients and methods: We conducted a retrospective study of 18 patients with a presumptive diagnosis of ADEM. Symptoms, imaging findings, progress and treatment were analysed.
Encefalomielitis aguda diseminada
Acute disseminated encephalomyelitis and ulcerative colitis: description of a clinical case in magnetic resonance. ISSN Acute disseminated encephalomyelitis ADEM is an acute demyelinatingdisorder of the central nervous system, characterized by an acute or subacute onset of neurological symptoms and focal signs in association with multifocal demyelinating findings on neuroimaging. Spontaneous resolution has been reported within days of onset, corticosteroids therapy accelerates the resolution time.